Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2

Summary: SARS-CoV-2 Omicron BA.2.75 has diversified into multiple subvariants with additional spike mutations and several are expanding in prevalence, particularly CH.1.1 and BN.1. Here, we investigated the viral receptor affinities and neutralization evasion properties of major BA.2.75 subvariants...

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Hlavní autoři:	Qian Wang, Zhiteng Li, Yicheng Guo, Ian A. Mellis, Sho Iketani, Michael Liu, Jian Yu, Riccardo Valdez, Adam S. Lauring, Zizhang Sheng, Aubree Gordon, Lihong Liu, David D. Ho
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-11-01
Edice:	iScience
Témata:	SARS-CoV-2 BA.2.75 subvariants evolutionary trajectories convergent evolution neutralizing monoclonal antibody mRNA vaccine
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589004223023313
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