Structural basis of human PRPS2 filaments

Abstract Background PRPP synthase (PRPS) transfers the pyrophosphate groups from ATP to ribose-5-phosphate to produce 5-phosphate ribose-1-pyrophosphate (PRPP), a key intermediate in the biosynthesis of several metabolites including nucleotides, dinucleotides and some amino acids. There are three PR...

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Principais autores:	Guang-Ming Lu, Huan-Huan Hu, Chia-Chun Chang, Jiale Zhong, Xian Zhou, Chen-Jun Guo, Tianyi Zhang, Yi-Lan Li, Boqi Yin, Ji-Long Liu
格式:	Artigo
語言:	Inglês
出版:	BMC 2023-05-01
叢編:	Cell & Bioscience
主題:	PRPS PRPP Cytoophidium hPRPS2 Cryo-EM Allosteric regulation
在線閱讀:	https://doi.org/10.1186/s13578-023-01037-z
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