Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway

Liver fibrosis is a repair response process after chronic liver injury. During this process, activated hepatic stellate cells (HSCs) will migrate to the injury site and secrete extracellular matrix (ECM) to produce fibrous scars. Clearing activated HSCs may be a major strategy for the treatment of l...

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Egile Nagusiak:	Sumin Sun, Sheng Huan, Zhanghao Li, Yue Yao, Ying Su, Siwei Xia, Shijun Wang, Xuefen Xu, Jiangjuan Shao, Zili Zhang, Feng Zhang, Jinbo Fu, Shizhong Zheng
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	PeerJ Inc. 2022-05-01
Saila:	PeerJ
Gaiak:	Curcumol Necroptosis ER stress Sirt1 NICD Liver fibrosis
Sarrera elektronikoa:	https://peerj.com/articles/13376.pdf
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