Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification

Abstract Rationale Vascular calcification is a prominent feature of late‐stage diabetes, renal and cardiovascular disease (CVD), and has been linked to adverse events. Recent studies in patients reported that plasma levels of osteomodulin (OMD), a proteoglycan involved in bone mineralisation, associ...

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Principais autores:	Nikolaos T. Skenteris, Till Seime, Anna Witasp, Eva Karlöf, Grzegorz B. Wasilewski, Marina A. Heuschkel, Armand M.G. Jaminon, Loureen Oduor, Robert Dzhanaev, Malin Kronqvist, Mariette Lengquist, Frederique E.C.M. Peeters, Magnus Söderberg, Rebecka Hultgren, Joy Roy, Lars Maegdefessel, Hildur Arnardottir, Eva Bengtsson, Isabel Goncalves, Thomas Quertermous, Claudia Goettsch, Peter Stenvinkel, Leon J. Schurgers, Ljubica Matic
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2022-02-01
Series:	Clinical and Translational Medicine
Assuntos:	aortic valves atherosclerosis calcification chronic kidney disease osteogenic transdifferentiation osteomodulin
Acceso en liña:	https://doi.org/10.1002/ctm2.682
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