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Relating the molecular phenotype of ulcerative colitis to the clinical course

Abstract The expanding portfolio of targeted therapies for ulcerative colitis (UC) suggests that a more precise approach to defining disease activity will aid clinical decision-making. This prospective study used genome-wide microarrays to characterize gene expression in biopsies from the most infla...

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Furkejuvvon:
Váldodahkkit: Katelynn S. Madill-Thomsen, Jeffery M. Venner, Denise E. Parsons, Konrad S. Famulski, Aducio L. Thiesen, Sami Hoque, Karen I. Kroeker, Karen Wong, Farhad Peerani, Levinus A. Dieleman, Frank Hoentjen, Daniel C. Baumgart, Philip F. Halloran, Brendan P. Halloran
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2025-03-01
Ráidu:Scientific Reports
Fáttát:
Inflammatory bowel disease
Molecular classifier
Machine learning
Molecular landscape
Disease activity
Liŋkkat:https://doi.org/10.1038/s41598-025-90618-8
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