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Genomic profiling in GIST: Implications in clinical outcome and future challenges

Gastrointestinal Stromal Tumors (GIST) are the most frequent mesenchymal neoplasia of the digestive tract. Genomic alterations in KIT, PDFGRA, SDH, and BRAF genes are essential in GIST oncogenesis. Therefore, the mutations in these genes have demonstrated clinical implications. Tumors with deletions...

Deskribapen osoa

Gorde:
Egile Nagusiak: German Calderillo-Ruíz, Eloy Andrés Pérez-Yepez, María Alejandra García-Gámez, Oliver Millan-Catalan, Consuelo Díaz-Romero, Paul Ugalde-Silva, Rodrigo Salas-Benavides, Carlos Pérez-Plasencia, Berenice Carbajal-López
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-02-01
Saila:Neoplasia: An International Journal for Oncology Research
Gaiak:
GIST
Genomic profiling
Mutations
Treatment
KIT
PDGFRA
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S1476558623000829
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