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Inflammation Induces Changes in the Functional Expression of P-gp, BCRP, and MRP2: An Overview of Different Models and Consequences for Drug Disposition

The ATP-binding cassette (ABC) transporters play a key role in drug pharmacokinetics. These membrane transporters expressed within physiological barriers can be a source of pharmacokinetic variability. Changes in ABC transporter expression and functionality may consequently affect the disposition of...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Sonia Saib, Xavier Delavenne
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2021-09-01
Rangatū:Pharmaceutics
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1999-4923/13/10/1544
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