Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway

Abstract Commensal bacteria generate immensely diverse active metabolites to maintain gut homeostasis, however their fundamental role in establishing an immunotolerogenic microenvironment in the intestinal tract remains obscure. Here, we demonstrate that an understudied murine commensal bacterium, D...

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Autores principales:	Yanan Zhang, Shuyu Tu, Xingwei Ji, Jianan Wu, Jinxin Meng, Jinsong Gao, Xian Shao, Shuai Shi, Gan Wang, Jingjing Qiu, Zhuobiao Zhang, Chengang Hua, Ziyi Zhang, Shuxian Chen, Li Zhang, Shu Jeffrey Zhu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-02-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-024-45636-x
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