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Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice

Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory process by inducing the development of M2 macrophages. We investigated whether modulating STAT6 activity in macrophages using AS1517499, the specific STAT6 inhibitor, affects the restoration of homeostasis after...

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Váldodahkkit: Ye-Ji Lee, Kiyoon Kim, Minsuk Kim, Young-Ho Ahn, Jihee Lee Kang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-03-01
Ráidu:Biomolecules
Fáttát:
Liŋkkat:https://www.mdpi.com/2218-273X/12/3/447
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