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Effective management of 5-fluorouracil-induced coronary vasospasm allowing chemotherapy continuation: a single-center observational study

Abstract Background 5-fluorouracil (5-FU) is a widely used chemotherapy agent in gastrointestinal (GI) malignancies, but it can cause cardiotoxicity, most commonly manifesting as chest pain due to coronary vasospasm, often mimicking acute coronary syndrome. Adequate management of 5-FU-associated vas...

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Principais autores: Kinga Kolossváry, Krisztina Heltai, Borbála Székely, Gábor Rubovszky
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2026-06-01
Series:Cardio-Oncology
Assuntos:
Cardio-oncology
5-Fluorouracil
Cardiotoxicity
Coronary vasospasm
Calcium channel blocker
Nitrates
Acceso en liña:https://doi.org/10.1186/s40959-026-00526-7
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