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Androgens alter the heterogeneity of small extracellular vesicles and the small RNA cargo in prostate cancer

Abstract Proliferation and survival of prostate cancer cells are driven by the androgen receptor (AR) upon binding to androgen steroid hormones. Manipulating the AR signalling axis is the focus for prostate cancer therapy; thus, it is crucial to understand the role of androgens and AR on extracellul...

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Hoofdauteurs: Elena S. Martens‐Uzunova, Gina D. Kusuma, Stefania Crucitta, Hong Kiat Lim, Crystal Cooper, James E. Riches, Arun Azad, Takahiro Ochiya, Glen M. Boyle, Melissa C. Southey, Marzia Del Re, Rebecca Lim, Grant A. Ramm, Guido W. Jenster, Carolina Soekmadji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2021-08-01
Reeks:Journal of Extracellular Vesicles
Onderwerpen:
androgen
androgen receptor
enzalutamide
exosomes
extracellular RNA
extracellular vesicles
Online toegang:https://doi.org/10.1002/jev2.12136
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