Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

Maintenance of epigenetic modifiers is of utmost importance to preserve the epigenome and consequently appropriate cellular functioning. Here, we analyzed Polycomb group protein (PcG) complex integrity in response to heat shock (HS). Upon HS, various Polycomb Repressive Complex (PRC)1 and PRC2 subun...

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Bibliografische Detailangaben

Hauptverfasser:	Maria Azkanaz, Aida Rodríguez López, Bauke de Boer, Wouter Huiting, Pierre-Olivier Angrand, Edo Vellenga, Harm H Kampinga, Steven Bergink, Joost HA Martens, Jan Jacob Schuringa, Vincent van den Boom
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	eLife Sciences Publications Ltd 2019-06-01
Schriftenreihe:	eLife
Schlagworte:	Polycomb epigenetics heat shock protein quality control leukemia nucleolus
Online-Zugang:	https://elifesciences.org/articles/45205
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