Linking somatic mutations in cancer to the electronic properties of DNA

Abstract Oxidative stress, generated by both endogenous and exogenous agents, can cause DNA lesions that, if not repaired, accumulate as somatic mutations and can contribute to cancer initiation. Here, we explored this problem through the lens of DNA electronic properties, quantified by the vertical...

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Autors principals:	Benoît de Witte, Cyril Karamaoun, Pauline Hermans, Maxime Tarabichi, Fabrizio Pucci, Marianne Rooman
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-05-01
Col·lecció:	BMC Genomics
Matèries:	DNA nucleobase motifs Vertical ionization potentials Genome mutability Carcinogenesis Somatic mutations Germline mutations
Accés en línia:	https://doi.org/10.1186/s12864-026-12879-5
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