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Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients

Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppr...

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Hauptverfasser: Shahrbano Rostami, Fatemeh Nadali, Reza Alibakhshi, Farhad Zaker, Nahid Nasiri, Mehrdad Payandeh, Bahram Chahardouli, Ali Maleki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tehran University of Medical Sciences 2016-12-01
Schriftenreihe:International Journal of Hematology-Oncology and Stem Cell Research
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Online-Zugang:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/713
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