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Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation

ABSTRACT Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract without causing pathology. However, this fungus is also a common cause of mucosal and systemic infections when antifungal immune defenses become compromised. The activation of antifungal host defenses...

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Principais autores: Leandro José de Assis, Judith M. Bain, Corin Liddle, Ian Leaves, Christian Hacker, Roberta Peres da Silva, Raif Yuecel, Attila Bebes, David Stead, Delma S. Childers, Arnab Pradhan, Kevin Mackenzie, Katherine Lagree, Daniel E. Larcombe, Qinxi Ma, Gabriela Mol Avelar, Mihai G. Netea, Lars P. Erwig, Aaron P. Mitchell, Gordon D. Brown, Neil A. R. Gow, Alistair J. P. Brown
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-12-01
coleção:mBio
Assuntos:
Candida albicans
cell wall
β-1,3-glucan
protein kinase A
Mig1
Mig2
Acesso em linha:https://journals.asm.org/doi/10.1128/mbio.02605-22
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