Trimethyl-Chitosan Coated Gold Nanoparticles Enhance Delivery, Cellular Uptake and Gene Silencing Effect of EGFR-siRNA in Breast Cancer Cells

Purpose: Despite the promising therapeutic effects of gene silencing with small interfering RNAs (siRNAs), the challenges associated with delivery of siRNAs to the tumor cells in vivo, has greatly limited its clinical application. To overcome these challenges, we employed gold nanoparticles modified...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Leila Baghani, Niloofar Noroozi Heris, Fatemeh Khonsari, Sajad Dinarvand, Meshkat Dinarvand, Fatemeh Atyabi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-04-01
Цуврал:	Frontiers in Molecular Biosciences
Нөхцлүүд:	gold nanoparticles (AuNPs) trimethyl chitosan (TMC) EGFR-siRNA siRNA delivery breast cancer
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.871541/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!