Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer
<p>Abstract</p> <p>Background</p> <p>The inactivation of tumor suppressor genes (TSGs) by aberrant DNA methylation plays an important role in the development of malignancy. Since this epigenetic change is reversible, it is a potential target for chemotherapeutic intervention using an inhibitor of DN...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2008-05-01
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| Col·lecció: | BMC Cancer |
| Accés en línia: | http://www.biomedcentral.com/1471-2407/8/128 |
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