Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity

Single-nucleus RNA sequencing (snRNA-seq), an alternative to single-cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering its applications. Here, we present a robust technique for isolating nuclei across various tissue types...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jisun So, Olivia Strobel, Jamie Wann, Kyungchan Kim, Avishek Paul, Dominic J Acri, Luke C Dabin, Jungsu Kim, Gang Peng, Hyun Cheol Roh
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	eLife Sciences Publications Ltd 2025-01-01
Schriftenreihe:	eLife
Schlagworte:	snRNA-seq adipocytes obesity
Online-Zugang:	https://elifesciences.org/articles/97981
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!