The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.

In addition to large plexiform neurofibromas (pNF), NF1 patients are frequently disfigured by cutaneous neurofibromas (cNF) and are often afflicted with chronic pain and itch even from seemingly normal skin areas. Both pNFs and cNF consist primarily of benign hyperproliferating nonmyelinating Schwan...

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Bibliografische Detailangaben

Hauptverfasser:	Frank L Rice, George Houk, James P Wymer, Sara J C Gosline, Justin Guinney, Jianqiang Wu, Nancy Ratner, Michael P Jankowski, Salvo La Rosa, Marilyn Dockum, James R Storey, Steven L Carroll, Phillip J Albrecht, Vincent M Riccardi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2019-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://doi.org/10.1371/journal.pone.0216527
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