Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

Previously, we reconstituted a minimal functional kinetochore from recombinant Saccharomyces cerevisiae proteins that was capable of transmitting force from dynamic microtubules to nucleosomes containing the centromere-specific histone variant Cse4 (Hamilton et al., 2020). This work revealed two pat...

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Prif Awduron:	Elise Miedlar, Grace E Hamilton, Samuel R Witus, Sara J Gonske, Michael Riffle, Alex Zelter, Rachel E Klevit, Charles L Asbury, Yoana N Dimitrova, Trisha N Davis
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	eLife Sciences Publications Ltd 2025-05-01
Cyfres:	eLife
Pynciau:	mitosis centromere kinetochore microtubule tension nucleosome
Mynediad Ar-lein:	https://elifesciences.org/articles/105150
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