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Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

Abstract Background Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the i...

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Autori principali: Oluwadara Pelumi Omotayo, Siyethemba Bhengu, Kobus Venter, Yolandy Lemmer, Shayne Mason
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2025-06-01
Serie:Animal Models and Experimental Medicine
Soggetti:
brain
C3HeB/FeJ mice
cannabidiol (CBD)
dosage
intrabuccal administration
LC–MS/MS
Accesso online:https://doi.org/10.1002/ame2.12569
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