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Penetrative biomimetic nanovehicle boosts immunotherapy in triple-negative breast cancer via SOS1 blockade

Immunotherapy of triple-negative breast cancer (TNBC) is significantly hindered by the immunosuppressive tumor microenvironment (TME). Notably, tumor-associated macrophages (TAMs), which constitute the predominant infiltrating immune cell type in TNBC, represent a critical target for “turning off” i...

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Збережено в:
Автори: Jiaxin Zhang, Peng Xian, Chao Wang, Xier Pan, Yaoyao Du, Yunrong Nan, Qing Pu, Linghui Zou, Donovan Green, Shuting Ni, Kaili Hu
Формат: Artigo
Мова:Inglês
Опубліковано: KeAi Communications Co., Ltd. 2025-10-01
Серія:Asian Journal of Pharmaceutical Sciences
Предмети:
Son of sevenless 1
Triple-negative breast cancer
Tetrandrine
Docetaxel
Cilengitide
Liposome
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S1818087625000480
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