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Expression and role of specificity protein 1 in the sclera remodeling of experimental myopia in guinea pigs

AIM: To study the expression of collagen I and transcription factor specificity protein 1 (Sp1), a transforming growth factor-β1 (TGF-β1) downstream target, and reveal the impact of the TGF-β1-Sp1 signaling pathway on collagen remodeling in myopic sclera. METHODS: Seventy-five 1-week-old guinea pig...

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Autores principales: Bo Jiang, Zhang-You Wu, Zi-Cheng Zhu, Gen-Jie Ke, Yue-Chun Wen, Si-Qin Sun
Formato: Artigo
Lenguaje:Inglês
Publicado: Press of International Journal of Ophthalmology (IJO PRESS) 2017-04-01
Colección:International Journal of Ophthalmology
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Acceso en línea:http://www.ijo.cn/en_publish/2017/4/20170408.pdf
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