Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose

This research identified four amino acid residues (Leu174, Asn297, Tyr301, and Gln291) that contribute to substrate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei. Potential hotspots affecting substrate specificity were selected through homology modeling, evoluti...

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Autori principali:	Wei Ma, Shiyu Yuan, Zixian Wang, Kangle Niu, Fengyi Li, Lulu Liu, Lijuan Han, Xu Fang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co., Ltd. 2024-12-01
Serie:	Engineering Microbiology
Soggetti:	Hexose transporter Glucose Galactose Mannose Transmembrane α-helix 7 Sugar transport
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2667370324000146
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