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Rapid paracellular transmigration of <it>Campylobacter jejuni</it> across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin

<p>Abstract</p> <p>Background</p> <p><it>Campylobacter jejuni</it> is one of the most important bacterial pathogens causing food-borne illness worldwide. Crossing the intestinal epithelial barrier and host cell entry by <it>C. jejuni</it> is considered the primary reason of damage to the intestinal...

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Principais autores: Boehm Manja, Hoy Benjamin, Rohde Manfred, Tegtmeyer Nicole, Bæk Kristoffer T, Oyarzabal Omar A, Brøndsted Lone, Wessler Silja, Backert Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-04-01
coleção:Gut Pathogens
Assuntos:
HtrA
E-cadherin
Fibronectin
MKN-28
Molecular pathogenesis
Cellular invasion
Signaling
TER
Virulence
Acesso em linha:http://www.gutpathogens.com/content/4/1/3
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