Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1β production in microglial cells following activation of β-adrenergic receptors

Endogenous noradrenaline (NA) has multiple bioactive functions and, in the central nervous system (CNS), has been implicated in modulating neuroinflammation via β-adrenergic receptors (β-ARs). Microglia, resident macrophages in the CNS, have a central role in the brain immune system and have been re...

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Hlavní autoři:	Hidetoshi Tozaki-Saitoh, Izumi Sasaki, Tomohiro Yamashita, Masako Hosoi, Takahiro A. Kato, Makoto Tsuda
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-07-01
Edice:	Journal of Pharmacological Sciences
Témata:	Microglia Inflammation Adrenergic receptor Intracellular signaling cascade
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1347861320300311
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