Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2

The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support for regenerating axons and to upregulation of inhibitory factors such as chondroitin sulphate proteoglycans including NG2 following injury. Lentiviral vector-mediated gene therapy is a possible strategy...

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Hlavní autoři:	Azim Patar, Peter Dockery, Siobhan McMahon, Linda Howard
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-03-01
Edice:	Biology
Témata:	ex vivo slice culture organotypic slice culture lentiviral vector spinal cord injury transection injury neurotrophin-3 short hairpin rna ng2 proteoglycan
On-line přístup:	https://www.mdpi.com/2079-7737/9/3/54
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