The Shigella Spp. Type III Effector Protein OspB Is a Cysteine Protease

ABSTRACT The type III secretion system is required for virulence of many pathogenic bacteria. Bacterial effector proteins delivered into target host cells by this system modulate host signaling pathways and processes in a manner that promotes infection. Here, we define the activity of the effector p...

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Autori principali:	Thomas E. Wood, Kathleen A. Westervelt, Jessica M. Yoon, Heather D. Eshleman, Roie Levy, Henry Burnes, Daniel J. Slade, Cammie F. Lesser, Marcia B. Goldberg
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2022-06-01
Serie:	mBio
Soggetti:	OspB Shigella TORC1 Tco89p catalytic dyad cysteine protease
Accesso online:	https://journals.asm.org/doi/10.1128/mbio.01270-22
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