Interferon-α improves phosphoantigen-induced Vγ9Vδ2 T-cells interferon-γ production during chronic HCV infection.

In chronic HCV infection, treatment failure and defective host immune response highly demand improved therapy strategies. Vγ9Vδ2 T-cells may inhibit HCV replication in vitro through IFN-γ release after Phosphoantigen (PhAg) stimulation. The aim of our work was to analyze Vγ9Vδ2 T-cell functionality...

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Principais autores:	Eleonora Cimini, Cécile Bonnafous, Veronica Bordoni, Eleonora Lalle, Helene Sicard, Alessandra Sacchi, Giulia Berno, Cristiana Gioia, Gianpiero D'Offizi, Ubaldo Visco Comandini, Chrysoula Vlassi, Maria Rosaria Capobianchi, Federico Martini, Chiara Agrati
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3358305?pdf=render
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