High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo
The TFAM-to-mtDNA ratio is critically important and must be maintained within a physiological range to allow normal mtDNA expression and prevent nucleoid hypercompaction in different mouse tissues. Mitochondrial transcription factor A (TFAM) is compacting mitochondrial DNA (dmtDNA) into nucleoids an...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Life Science Alliance LLC
2021-11-01
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| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101034 |
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