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Chronotoxicity of Acrylamide in Mice Fed a High-Fat Diet: The Involvement of Liver CYP2E1 Upregulation and Gut Leakage

Acrylamide (ACR) is produced under high-temperature cooking of carbohydrate-rich foods via the Maillard reaction. It has been reported that ACR has hepatic toxicity and can induce liver circadian disorder. A high fat diet (HFD) could dysregulate liver detoxification. The current study showed that ad...

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Autores principales: Luanfeng Wang, Yanhong Liu, Huajing Gao, Shuqi Ge, Xinru Yao, Chang Liu, Xintong Tan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-06-01
Colección:Molecules
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Acceso en línea:https://www.mdpi.com/1420-3049/28/13/5132
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