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Pneumocystis murina promotes inflammasome formation and NETosis during Pneumocystis pneumonia

ABSTRACT Pneumocystis jirovecii pneumonia (PjP) poses a serious risk to individuals with compromised immune systems, such as individuals with HIV/AIDS or undergoing immunosuppressive therapies for cancer or solid organ transplants. Severe PjP triggers excessive lung inflammation, resulting in lung f...

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Principais autores: Steven G. Sayson, Alan Ashbaugh, Aleksey Porollo, George Smulian, Melanie T. Cushion
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2024-08-01
סדרה:mBio
נושאים:
Pneumocystis
infectious disease
neutrophils
opportunistic fungi
immunity
Pneumocystis pneumonia
גישה מקוונת:https://journals.asm.org/doi/10.1128/mbio.01409-24
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