Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites

Abstract Malaria vaccination approaches using live Plasmodium parasites are currently explored, with either attenuated mosquito-derived sporozoites or attenuated blood-stage parasites. Both approaches would profit from the availability of attenuated and avirulent parasites with a reduced blood-stage...

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Detalhes bibliográficos

Principais autores:	Julia M Sattler, Lukas Keiber, Aiman Abdelrahim, Xinyu Zheng, Martin Jäcklin, Luisa Zechel, Catherine A Moreau, Smilla Steinbrück, Manuel Fischer, Chris J Janse, Angelika Hoffmann, Franziska Hentzschel, Friedrich Frischknecht
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2024-08-01
coleção:	EMBO Molecular Medicine
Assuntos:	Genetic Attenuation Malaria Plasmodium Vaccine Virulence
Acesso em linha:	https://doi.org/10.1038/s44321-024-00101-6
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