Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody Thresholds

The rise of SARS-CoV-2 variants has made the pursuit to define correlates of protection more troublesome, despite the availability of the World Health Organisation (WHO) International Standard for anti-SARS-CoV-2 Immunoglobulin sera, a key reagent used to standardise laboratory findings into an inte...

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Autores principales:	Diego Cantoni, Martin Mayora-Neto, Angalee Nadesalingam, David A. Wells, George W. Carnell, Luis Ohlendorf, Matteo Ferrari, Phil Palmer, Andrew C.Y. Chan, Peter Smith, Emma M. Bentley, Sebastian Einhauser, Ralf Wagner, Mark Page, Gianmarco Raddi, Helen Baxendale, Javier Castillo-Olivares, Jonathan Heeney, Nigel Temperton
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2022-03-01
Colección:	Frontiers in Immunology
Materias:	COVID-19 variants of concern correlates of protection (CoP) international standard disease severity 20/136
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.773982/full
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