CCR8 antagonist suppresses liver cancer progression via turning tumor-infiltrating Tregs into less immunosuppressive phenotype
Abstract Background Regulatory T cells (Tregs) are the main immunosuppressive cells in tumor immune microenvironment (TIME). However, systemic Treg depletion is not favored due to the crucial role of Tregs in the maintenance of immune homeostasis and prevention of autoimmunity. Recently, CCR8 has be...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
BMC
2025-04-01
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| Ráidu: | Journal of Experimental & Clinical Cancer Research |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1186/s13046-025-03286-x |
| Fáddágilkorat: |
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