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Spheroid Model of Mammary Tumor Cells: Epithelial–Mesenchymal Transition and Doxorubicin Response

Breast cancer is the most prevalent cancer among women worldwide. Therapeutic strategies to control tumors and metastasis are still challenging. Three-dimensional (3D) spheroid-type systems more accurately replicate the features of tumors in vivo, working as a better platform for performing therapeu...

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Principais autores: Laura Lacerda Coelho, Matheus Menezes Vianna, Debora Moraes da Silva, Beatriz Matheus de Souza Gonzaga, Roberto Rodrigues Ferreira, Ana Carolina Monteiro, Adriana Cesar Bonomo, Pedro Paulo de Abreu Manso, Marcelo Alex de Carvalho, Fernando Regla Vargas, Luciana Ribeiro Garzoni
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Biology
Fag:
breast cancer
three-dimensional cell culture
spheroids
doxorubicin
cell migration
epithelial–mesenchymal transition
Online adgang:https://www.mdpi.com/2079-7737/13/7/463
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