Optimal exposure targets for vancomycin in the treatment of neonatal coagulase-negative Staphylococcus infection: A retrospective study based on electronic medical records

Background: The currently advocated ratio of area under the curve (AUC) over 24 h to minimum inhibitory concentration (AUC/MIC) > 400 and AUC < 600 mg h/L as the therapeutic drug monitoring (TDM) target of vancomycin is based on data from multiple observational studies in adult patients with methici...

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Autori principali:	Quanyao Chen, Jun Wan, Wei Shen, Wanlong Lin, Xiuxian Lin, Zhiyi Huang, Min Lin, Yao Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-05-01
Serie:	Pediatrics and Neonatology
Soggetti:	area under the curve clinical effect nephrotoxicity vancomycin
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1875957222000110
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