Ligand Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies of Asymmetrical Hexahydro-2H-Indazole Analogs of Curcumin (AIACs) to Discover Novel Estrogen Receptors Alpha (ERα) Inhibitor

The estrogen receptor alpha (ERα) plays an important role in breast development and pro-proliferation signal activation in the normal and cancerous breast. The ERα inhibitors were potentially active as cytotoxic agents against breast cancer. This study was conducted in order to find Asymmetrical Hex...

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Bibliografski detalji

Glavni autori:	Hariyanti Hariyanti, Kusmadi Kurmardi, Arry Yanuar, Hayun Hayun
Format:	Artigo
Jezik:	Inglês
Izdano:	Department of Chemistry, Universitas Gadjah Mada 2020-11-01
Serija:	Indonesian Journal of Chemistry
Teme:	asymmetric hexahydro-2h-indazole analogs of curcumin aiacs estrogen receptor alpha inhibitor erα inhibitor pharmacophore modeling molecular docking breast cancer
Online pristup:	https://jurnal.ugm.ac.id/ijc/article/view/54745
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