Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

This study aimed at delivering intranasal zolmitriptan directly to the brain through preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal mucociliary transit time. Zolmitriptan-loaded bilosomes were constructed through a thin film hydration method applying Box–Be...

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Hlavní autoři:	Mai M. El Taweel, Mona H. Aboul-Einien, Mohammed A. Kassem, Nermeen A. Elkasabgy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-11-01
Edice:	Pharmaceutics
Témata:	zolmitriptan intranasal bilosomes sodium deoxycholate mucoadhesive gel brain targeting
On-line přístup:	https://www.mdpi.com/1999-4923/13/11/1828
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