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Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells

Obesity has been associated with the development of 13 different types of cancers, including breast cancer. Evidence has indicated that cancer-associated adipocytes promote the proliferation, invasion, and metastasis of cancer. However, the mechanisms that link CAAs to the progression of obesity-rel...

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Autori principali: Liangge Li, Jiafeng Geng, Wen Yu, Feifei Zhou, Zhihuan Zheng, Kaiyue Fu, Junjie Kong, Xiujing Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-08-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2023.1205030/full
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