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What is Rate-Limiting During Sustained Synaptic Activity: Vesicle Supply or the Availability of Release Sites

For some types of synapses the availability of release-ready vesicles is a limiting factor during ongoing activity. Synaptic strength in this case is determined both by the recruitment of such vesicles and the probability of their release during an action potential. Here it is argued that not the av...

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Detalhes bibliográficos
Autor principal: Erwin Neher
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2010-09-01
coleção:Frontiers in Synaptic Neuroscience
Assuntos:
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00144/full
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