Mutation on lysX from Mycobacterium avium hominissuis impacts the host–pathogen interaction and virulence phenotype

The lysX gene from Mycobacterium avium hominissuis (MAH) is not only involved in cationic antimicrobial resistance but also regulates metabolic activity. An MAH lysX deficient mutant was shown to exhibit a metabolic shift at the extracellular state preadapting the bacteria to the conditions inside h...

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Podrobná bibliografie

Hlavní autoři:	Greana Kirubakar, Hubert Schäfer, Volker Rickerts, Carsten Schwarz, Astrid Lewin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2020-12-01
Edice:	Virulence
Témata:	virulence mycobacterium avium hominissuis nontuberculous mycobacteria galleria mellonella infection model multinucleated giant cells pathogenesis lysx (lysyl-trna synthetase) host-pathogen interaction inflammatory cytokines
On-line přístup:	http://dx.doi.org/10.1080/21505594.2020.1713690
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