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The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming

Acute myocardial infarction (MI) is a leading cause of morbidity and mortality, and therapeutic options remain limited. Endogenously generated nitric oxide (NO) is highly cardioprotective, but protection is not replicated by nitroso-vasodilators (e.g., nitrates, nitroprusside) used in clinical pract...

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Kaydedildi:
Asıl Yazarlar: Zachary W Grimmett, Rongli Zhang, Hua-Lin Zhou, Qiuying Chen, Dawson Miller, Zhaoxia Qian, Justin Lin, Riti Kalra, Steven S Gross, Walter J Koch, Richard T Premont, Jonathan S Stamler
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications Ltd 2025-11-01
Seri Bilgileri:eLife
Konular:
S-nitrosylation
denitrosylase
myocardial infarction
metabolic reprogramming
ischemia–reperfusion
Online Erişim:https://elifesciences.org/articles/106601
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