Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation Sequencing

MicroRNA (miRNA) has emerged as an important regulator of gene expression in neurodegenerative disease as amyotrophic lateral sclerosis (ALS). In the nervous system, dysregulation in miRNA-related pathways is subordinated to neuronal damage and cell death, which contributes to the expansion of neuro...

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Hlavní autoři:	Bruna De Felice, Francesco Manfellotto, Giuseppe Fiorentino, Anna Annunziata, Elio Biffali, Raimondo Pannone, Antonio Federico
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-08-01
Edice:	Frontiers in Genetics
Témata:	amyotrophic lateral sclerosis microRNAs neurodegenerative diseases NGS data analysis sporadic ALS
On-line přístup:	https://www.frontiersin.org/article/10.3389/fgene.2018.00310/full
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