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Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity

The hormone leptin is known to robustly suppress food intake by acting upon the leptin receptor (LepR) signaling system residing within the agouti-related protein (AgRP) neurons of the hypothalamus. However, clinical studies indicate that leptin is undesirable as a therapeutic regiment for obesity,...

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Bibliografische gegevens
Hoofdauteurs: Yong Han, Yang He, Lauren Harris, Yong Xu, Qi Wu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2023-04-01
Reeks:eLife
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Online toegang:https://elifesciences.org/articles/82649
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