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Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria

Abstract Bacterial primase initiates the repeated synthesis of short RNA primers that are extended by DNA polymerase to synthesize Okazaki fragments on the lagging strand at replication forks. It remains unclear how the enzyme recognizes specific initiation sites. In this study, the DnaG primase fro...

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Bibliografiske detaljer
Principais autores: Yingqin Zhou, Hao Luo, Zhongchuan Liu, Mu Yang, Xiaoyun Pang, Fei Sun, Ganggang Wang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2017-04-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-017-00767-8
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