Multifaceted role of serine hydroxymethyltransferase in health and disease

ABSTRACT: Serine hydroxymethyltransferase (SHMT) is a key enzyme in 1-carbon metabolism, a biochemical pathway critical for cellular growth, proliferation, and survival. One-carbon metabolism integrates the folate and methionine cycles to produce essential intermediates necessary for nucleotide synt...

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Detalhes bibliográficos

Principais autores:	Jing Zhang, Seong Eun Lee, Jiyeon Yoon, Bon Jeong Ku, Junyoung O. Park, Da Hyun Kang, Jun Young Heo, Yea Eun Kang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	Molecules and Cells
Assuntos:	Cancer Metabolic disease Neurological disorders One-carbon metabolism Serine hydroxymethyltransferase
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S101684782500086X
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