Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE

The ability of the bacterial pathogen Pseudomonas aeruginosa to cause both chronic and acute infections mainly relies on its capacity to finely modulate the expression of virulence factors through a complex network of regulatory circuits, including the pqs quorum sensing (QS) system. While in most Q...

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Detalhes bibliográficos

Principais autores:	Valerio Baldelli, Francesca D’Angelo, Viola Pavoncello, Ersilia Vita Fiscarelli, Paolo Visca, Giordano Rampioni, Livia Leoni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2020-12-01
Colecção:	Virulence
Assuntos:	pseudomonas aeruginosa antivirulence strategy quorum sensing inhibition nitrofurazone erythromycin estolate screening pqse
Acesso em linha:	http://dx.doi.org/10.1080/21505594.2020.1770508
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