The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer

Abstract Background Posttranscriptional modification of tumor-associated factors plays a pivotal role in breast cancer progression. However, the underlying mechanism remains unknown. M6A modifications in cancer cells are dynamic and reversible and have been found to impact tumor initiation and progr...

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Detalhes bibliográficos

Principais autores:	Youqin Xu, Mu Song, Ziyang Hong, Wancheng Chen, Qianbing Zhang, Jianlong Zhou, Chao Yang, Zilong He, Juanjuan Yu, Xiaolin Peng, Qiuhong Zhu, Shaotian Li, Kaiyuan Ji, Minfeng Liu, Qiang Zuo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-01-01
coleção:	Journal of Experimental & Clinical Cancer Research
Assuntos:	Breast cancer METTL3 LATS1 Hippo-YAP/TAZ signaling pathway
Acesso em linha:	https://doi.org/10.1186/s13046-022-02581-1
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