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Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma

Abstract Background The poor chemo-response and high DNA methylation of ovarian clear cell carcinoma (OCCC) have attracted extensive attentions. Recently, we revealed the mutational landscape of the human kinome and additional cancer-related genes and found deleterious mutations in ARID1A, a compone...

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Autors principals: Shang Li, Gert Jan Meersma, Jolanta Kupryjanczyk, Steven de Jong, G. Bea A. Wisman
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-06-01
Col·lecció:Journal of Translational Medicine
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Accés en línia:https://doi.org/10.1186/s12967-024-05311-7
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